Open Access Open Access  Restricted Access Subscription Access

Evaluation of Antimicrobial Potential of Anisochilus carnosus L. (Wall)

Reshi N A, Raytekar N A

Abstract


An investigation was carried out to assess the antimicrobial potential of Anisochilus carnosus against Proteus vulgaris, E. coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Candia albicans, Microsporum canis, Microsporum gypseum and Alternaria alternata. Aqueous and different organic solvent extracts were screened against test microorganisms by Disc diffusion method followed by determination of Minimum inhibitory concentration (MIC) of the active extracts by two fold serial dilution method. Significant antibacterial activity was observed in methanol extract against P. aeruginosa with 36±0.42 mm zone of inhibition and MIC value of 0.32 mg/ml. Ethyl acetate exhibited the maximum antifungal property against A. alternata with the maximum of 32±0.52 mm zone of inhibition and MIC value of 0.45 mg/ml. The study confirms the presence of potent antimicrobial agents in A. carnosus.


Full Text:

PDF

References


Almagboul AZ, Bashir AK, Farouk A, Salih AKM (1985), “Antimicrobial activity of certain Sudanese plants used in folkloric medicine. Screening for antibacterial activity”, Fitoterapia, Volume 56, pp. 331−337.

Mahesh B, Satish S (2008), “Antimicrobial activity of some important medicinal plant extract against plant and human pathogens”, World J. of Agri.Sci., Volume 4, pp. 839−843.

Gopalkrishnan S, George S, Benny PJ (2010), “Antimicrobial effect of Punica grantum on pyogenic bacteria”, J. of Pharma and Biomed Sci., Volume 3, Issue 6, pp. 81−86.

Jain SC, Jian R, Vlietinck JA (2004), “In vitro and in vivo antimicrobial efficacy of Mimosa hamate”, Indian J Biotechnology, Volume 3, pp. 271−273.

Buwa LV, Staden JV (2006), “Antibacterial and antifungal activity of traditional medicinal plants used against venereal diseases in South Africa. J.of Ethnopharmacol, Volume 103, pp. 139−142.

Usman AK, Hazir R, Zeeshan N, Muhammad Q, Jafar K, Bushra R (2013), “Antibacterial activity of some medicinal plants against selected human pathogenic bacteria”, Eur J MicrobiolImmunol., Volume 3, pp. 272−274.

Muthuraman MS, Santharam L, Ariraman S, Pemaiah B (2012), “Studies on anticancer and antimicrobial efficacy of Anisochilus carnosus extracts”, International Journal of Pharmacy and Pharmaceutical Science, Volume 4, Issue 2, pp. 132−135.

Kumar AS, Samanta KC, Chipa RC (2010), “Hepatoprotective activity of alcoholic and aqueous extracts of leaves of Anisochilus carnosus (Linn.) Wall”, International Journal of Pharmacy and Life Sciences, Volume 1, Issue 2, pp. 99−104.

Kulandhaivel M, Sooraj SN, Nathiya K, Palaniswamy M (2011), “Antifungal activity and phytochemical screening of Anisochilus carnosus and Melaleuca alternifolia against opportunistic pathogen Candida albicans”, International Journal of Pharmaceutical and Biological Archives, Volume 2, Issue 6, pp. 1668−1670.

Subramanian SS, Nair AGR (1972), “Flavonoids of the leaves of Mentha spicata and Anisochilus carnosus”, Phytochemistry, Volume 11, Issue 1, pp. 452−453.

Harborne JB (1998), “Phytochemical Methods-A guide to modern techniques of plant analysis”, Chapman and Hall, pp. 182−190. London

Suffredini JB, Sader HS, Goncalves AG, Reis AO, Gales AC, Varella AD and Younes RN (2004), “Screening of antimicrobial extracts from plants native to Brazilian Amazon rainforest and Atlantic forest Brazil”, Journal of Medical and Biological Research, Volume 37, pp. 379−384.

Anonymous (1996), “Pharmacopeia of India (The Indian Pharmacopeia), 3rd Edn., Govt. of India, New Delhi, Ministry of Family and Health Welfare.

Hoffman BR, Delas AH, Blanco K, Wiederhold N, Lewis RE and Williams L (2004), “Screening of antibacterial and antifungal activities of ten medicinal plants from Ghana”, Pharmaceutical Biology, Volume 42, Issue 1, pp. 13−17

Klancnik A, Piskernik S, Jeršek B, Mozina SS (2010), “Evaluation of diffusion and dilution methods to determine the antibacterial activity of plant extracts”, Journal of Microbiological Methods, Volume 81, Issue 2, pp. 121−126.

Johnson M, Wesely EG, Kavitha MS, Uma V (2011), “Antibacterial activity of leaves and inter- nodal callus extracts of Mentha arvensis L”, Asian Pacific journal of tropical Medicine, Volume 4, Issue 3, pp. 196−200.

Raveesha KA (2015), “Evaluation of antifungal potential of selected medicinal plants against human pathogenic fungi”, International Journal of Green Pharmacy, Volume 9, Issue 2, pp. 110−117.

Leven M, Vanden Berghe DA, Mertens F, Vlietinck A, Lammens E (1979), “Screening of higher plants for biological activities-Antimicrobial activity”, Planta Medica, Volume 36, pp. 311−321.

Naqvi SAH, Khan MSY, Vohora SB (1991), “Antibacterial, anti-fungal and anthelmintic investigations on Indian medicinal plants”, Fitoterapia, Volume 62, pp. 221–228.

Heisey RM, Gorham BK (1992), “Antimicrobial elects of plant extracts on Streptococcus mutans, Candida albicans, Trichophyton rubrum and other microorganisms”, Letters in Applied Microbiology, Volume 14, pp. 136–139.

Ficker CE, Arnason JT, Vindas PS, Alvarez LP, Akpagana K, Gbeassor M, Smith, ML (2003), “Inhibition of human pathogenic fungi by ethno botanically selected plant extracts”, Mycoses, Volume 46, Issue 1−2, pp. 29−37.

Murugan S, Uma Devi P, Parameswari NK, Mani KR (2011), “Antimicrobial activity of S. jambos against selected human pathogens”, Int J Pharm PharmSci, Volume 3, pp. 44−47.


Refbacks

  • There are currently no refbacks.