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The Impact of Alcohol Consumption on Prostate Cancer

Livingstone Aduse-Poku, Joseph Inungu, Priscilla Aba Aggrey

Abstract


There have been conflicting findings on alcohol consumption and risk of prostate cancer. Some studies have shown significant association between alcohol consumption and risk of prostate cancer but different relationships exist for heavy drinking, light drinking and abstinence. The purpose of the study is to perform an analysis of the relationship between alcohol consumption and risk of breast cancer adult males in the United States. A cross-sectional study 15,071 adult males was done using the National Health Interview Survey (NHIS) sample adult data in the USA. The variables collected included prostate cancer, number of drinks, race, drinking status, marital status, employment status, high blood pressure and high cholesterol level. Data was analyzed using IBM Statistical Package for the Social Sciences (SPSS) for windows, version 25.0. Abstaining from alcohol decreased the odds of prostate cancer by 11% (95% CI: 0.21-2.54) compared to the odds of prostate cancer in men who take more than 5 drinks in a week. After adjusting for race, alcohol consumption level, marital status, work status, high blood pressure, high cholesterol level, and smoking status, the odds of prostate decreased by 15% [AOR (95% CI): 0.44-0.97)] in men who abstained from alcohol compared to the odds of prostate cancer in men who take more than 5 drinks in a week. The relationship between alcohol and prostate cancer has been inconsistent. This study found a possible positive relationship between alcohol use and risk of prostate cancer. High blood pressure and cholesterol were also found to be associated with prostate cancer risk.

 


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References


Global cancer statistics (2018), “GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries”.

Bray F, Ferlay J, Soerjomataram I, Siegel R, Torre L, Jemal A (2018), “Global cancer statistics GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries”, CA: A Cancer Journal for Clinicians, Volume 68, Issue 6, pp. 394−424.

Fenton J, Weyrich M, Durbin S, Liu Y, Bang H, Melnikow J (2018), “Prostate-Specific Antigen–Based Screening for Prostate Cancer: Evidence Report and Systematic Review for the US Preventive Services Task Force”, JAMA, Volume 319, Issue 18, pp. 1914−1931.

World Health Organization (2016), “Global status report on alcohol and health”.

Dickerman B, Markt A, Koskenvuo S, Pukkala C, Mucci M, Kaprio E (2016), “Alcohol intake, drinking patterns, and prostate cancer risk and mortality: A 30-year prospective cohort study of Finnish twins”, Cancer Causes & Control, Volume 27, Issue 9, pp. 1049−1058.

Breslow RA, Weed DL (2016), “Review of Epidemiologic Studies of Alcohol and Prostate Cancer”, Cancer, Volume 30, pp. 1–13.

Demoury, Karakiewicz, Parent (2016), “Association between lifetime alcohol consumption and prostate cancer risk: A case-control study in Montreal, Canada”, Cancer Epidemiology, Volume 45, pp. 11−17.

Zhao J, Stockwell T, Roemer A, Chikritzhs T (2016), “Is alcohol consumption a risk factor for prostate cancer? A systematic review and meta-analysis”, BMC Cancer, Volume 16, Issue 1, pp. 845.

Watters J, Park Y, Hollenbeck A, Schatzkin A, Albanes D (2010), “Alcoholic Beverages and Prostate Cancer in a Prospective US Cohort Study”, American Journal of Epidemiology, Volume 172, Issue 7, pp. 773−780.

Li et al. (2012), “Recent trends in prostate cancer testing and incidence among men under age of 50”, Cancer Epidemiology, Volume 36, Issue 2, pp. 122−127.

Hayes B, Dennis L (2001), “Alcohol and prostate cancer”, Epidemiology Rev, Volume 23, pp. 110–114.

Fowke JH, Howard L, Andriole GL, Freedland SJ, “Alcohol intake increases high grade prostate cancer risk among men taking dutasteride in the REDUCE trial”, Eur. Urol, Available from: http://dx.doi.org/10.1016/ j. eururo.2014.01.037.

Miles FL, Neuhouser ML, Zhang Z (2018), “Concentrated sugars and incidence of prostate cancer in a prospective cohort”, British Journal of Nutrition, Volume 120, Issue 6, pp. 703−710. doi:10.1017/S0007114518001812.

Bonilla et al. (2016), “Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort”, BMC Medicine, Volume 14, Issue 66,

Jones (1999-2010), “Cigarette Smoking and Prostate Cancer Mortality in Four US States”, Preventing Chronic Disease., Volume 13, pp. 1−10.

Haas GP, Delongchamps N, Brawley OW, Wang CY, Roza G (2008), “The worldwide epidemiology of prostate cancer: perspectives from autopsy studies”, Can J Urol, Volume 15, pp. 3866–3871.

Jacob S, Khan T, Lee L (2017), “The Effect of Green Tea Consumption on Prostate Cancer Risk and Progression: A Systematic Review”, Nutrition and Cancer, Volume 69, Issue 3, pp. 353−364.

Shephard R (2017), “Physical Activity and Prostate Cancer: An Updated Review”, Sports Medicine, Volume 47, Issue 6, pp. 1055−1073. doi:10.1007/s40279-016-0648-0.

Reuter J, Gupta N, Chaturvedi B, Aggarwal K, “Oxidative stress, inflammation, and cancer: How are they linked?”, Free Radical Biology and Medicine, Volume 49, Issue 11, pp. 1603−1616.

(2010), “Oxidative stress, inflammation, and cancer: How are they linked?”, Free Radical Biology and Medicine, Volume 49, Issue 11, pp. 1603−1616.

Fowke et al. Ramadas, Kunnambath, Potter, John D (2015), “Associations of Body Mass Index, Smoking, and Alcohol Consumption With Prostate Cancer Mortality in the Asia Cohort Consortium”, American Journal of Epidemiology, Volume 182, Issue 5, pp. 381−389.

Martin, et al. (2018), “Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial”, JAMA, Volume 319, Issue 9, pp. 883−895.

Lloyd S, Jie H, Gohlke S, Vasanta P, Shaiju K, Rebeca S (2018), “Metabolomic landscape of African American prostate cancer: Insights into the biologic basis of the racial disparity”, American Association for Cancer Research, Volume 10, Issue 1158, pp. 1538−7755.

Jensen et al. (2005), “Cancer Epidemiology and Prevention”, Oxford University Press, pp. 290–318, New York.

Sesso H, Paffenbarger R, Lee I (2001), “Alcohol consumption and risk of prostate cancer: The Harvard Alumni Health Study”, International Journal of Epidemiology, Volume 30, Issue 4, pp. 749−755.

Jiang L, Yang K, Tian J, Guan Q, Yao N, Cao N, Yang S (2010), “Efficacy of antioxidant vitamins and selenium supplement in prostate cancer prevention: a meta-analysis of randomized controlled trials”, Nutrition & Cancer, Volume 62, Issue 6, pp. 719−727. doi:10.1080/01635581.2010.494335.

Martin R, Vatten M, Gunnell L, Romundstad D (2010), “Blood pressure and risk of prostate cancer: Cohort Norway (CONOR)”, Cancer Causes & Control, Volume 21, Issue 3, pp. 463−472.

Gann PH, Daviglus ML, Dyer AR, Stamler J (2000), “Heart rate and prostate cancer mortality: results of a prospective analysis”, Cancer Epidemiol Biomarkers Prev., Volume 4, Issue 6, pp. 611–616.

Heir T, Falk R, Robsahm T, Sandvik L, Erikssen J, Tretli S (2016), “Cholesterol and prostate cancer risk: A long-term prospective cohort study”, BMC Cancer, Volume 16, Issue 1, pp. 643.


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