Open Access
Subscription Access
Environmental Factors on Secondary Metabolism of Medicinal Plants
Abstract
Plants are unrivaled in the common world in both the number and unpredictability of secondary metabolites they produce, and the pervasive phenylpropanoids and the heredity explicit glucosinolates speak to two such vast and artificially various gatherings. Advances in genome-empowered natural chemistry and metabolomic innovations have incredibly expanded the comprehension of their metabolic systems in assorted plant species. There additionally has been some advancement in explaining the quality administrative systems that are critical to their combination, gathering and capacity. Secondary metabolites have essential defense and flagging jobs, and they add to the general quality of creating and aging natural products. Particularly, light conditions and temperature are exhibited to have an unmistakable job on the organization of phenolic compounds. The present survey centers around the examinations on components related with the guideline of key secondary metabolites, mostly phenolic compounds, in different plants are a helpful cluster of normal items as well as an essential piece of plant defense framework against pathogenic assaults and environmental stresses. With astounding biological exercises, plant SMs are progressively utilized as drug fixings and nourishment added substances for remedial, fragrant and culinary purposes. Different hereditary, ontogenic, morphogenetic and environmental components can impact the biosynthesis and aggregation of SMs. As indicated by the writing reports, for instance, SMs gathering is unequivocally reliant on an assortment of environmental factors, for example, light, temperature, soil water, soil richness and saltiness, and for most plants, an adjustment in an individual factor may modify the substance of SMs regardless of whether different elements stay steady. Here, we survey with accentuation how every one of single elements to influence the collection of plant secondary metabolites, and lead a relative examination of applicable normal items in the stressed and unstressed plants. Hopefully, this narrative survey will diagram a general picture of environmental elements in charge of change in plant SMs, give a handy method to get reliable quality and high amount of bioactive compounds in vegetation, and present a few proposals for future innovative work.
References
David. L. Nelson, Michael (2013), “Lehninger Principles of Biochemistry”, 6th Edition M. Cox Publisher: W.H. Freeman,
Donald Voet, Judith G. Voet, Charlotte W (2016), “Fundamentals of Biochemistry: Life at the Molecular Level”, Pratt Publisher: Hoboken, NJ: John Wiley & Sons,
Trease, Evans Pharmacognosy William Charles Evans, Daphne Evans, George Edward Trease Publisher: St. Louis: Elsevier Health Sciences UK, 2014.
James E Robbers; Marilyn K Speedie; Varro E Tyler (1996), “Pharmacognosy and Pharmacobiotechnology”, Baltimore: Williams & Wilkins,
Michael Heinrich; Joanne Barnes; Simon Gibbons; Elizabeth M Williamson (2012), “Fundamentals of Pharmacognosy and Phytotherapy”, Churchill Livingstone,
Medicinal Plants: Ethno-Uses to Biotechnology Era Author: Aly Farag El Sheikha Affiliation: Department of Biology, McMaster University, 1280 Main St. West, Hamilton, ON, L8S 4K1, Canada
Medicinal Plants: Chemistry and Properties M Daniel Publisher: CRC Press, Apr 19, 2016
Giweli, A. A., Džamić, A. M., Soković, M., Ristić, M., Janaćković, P., Marin, P, (2013), “The Chemical Composition, Antimicrobial and Antioxidant Activities of the Essential Oil of Salvia fruticosa Growing Wild in Libya”, Archives of Biological Sciences, Volume 1, Issue 65, pp. 321−329.
Bruno Leite Sampaio, RuAngelie Edrada-Ebel, Fernando Batista Da Costa, “Effect of the environment on the secondary metabolic profile of Tithonia diversifolia: a model for environmental metabolomics of plants”, Sci Rep. 2016; 6: 29265. doi: [10.1038/srep29265] PMCID: PMC4935878 PMID: 27383265
Claire Brittain, Claire Kremen, Andrea Garber, Alexandra-Maria Klein (2014), “Pollination and Plant Resources Change the Nutritional Quality of Almonds for Human Health PLoS One”, Volume 9, Issue 2, e90082. doi: [10.1371/journal.pone.0090082] PMCID: PMC3937406 PMID: 24587215
Koppert Biological System Why do pollinators visit flowers? URL: https://www.koppert.com/pollination/natural-pollination-bumble-bees/why-do-pollinators-visit-flowers/
Ferris Jabr Farming a Toxin to Keep Crops Healthy Scientific American The Sciences September 3, 2013 Available From: https://www.scientificamerican.com/article/farming-a-toxin/
Forest Health Handbook North Carolina Forest Service 3rd Edition Publisher: Ryan A. Blaedow September 2011
Crop Scouting Manual (2010), Field Crop Integrated Pest Management Program - University of Wisconsin-Extension - Cooperative Extension Service
Douglas J. Futuymaa, Anurag A Agrawal (Oct 27 2009), “Macroevolution and the biological diversity of plants and herbivores”, Proc Natl Acad Sci U S A., Volume 106. Issue 43, pp. 18054–18061. doi: [10.1073/pnas.0904106106] PMCID: PMC2775342 PMID: 19815508
Marcia O. Mello, Marcio C (May/Aug. 2002), “Silva-Filho Plant-insect interactions: an evolutionary arms race between two distinct defense mechanisms”, Braz. J. Plant Physio, Volume 14, Issue 2, Londrina http://dx.doi.org/10.1590/S1677-04202002000200001
Plant Evolutionary Biology Copyright Publisher Name Springer, Dordrecht Information Springer Science+ Business Media B.V. 1988 DOI https://doi.org/10.1007/978-94-009-1207-6
Neeraj Jain, Rajani S. Nadgauda Commiphora wightii (Arnott) Bhandari (2013), “A Natural Source of Guggulsterone: Facing a High Risk of Extinction in Its Natural Habitat”, American Journal of Plant Sciences, Volume 4, Issue 6A, pp. 57−68, doi: 10.4236/ajps.2013.46A009.
Nakuleshwar Dut Jasuja, Jyoti Choudhary, Preeti Sharama, Nidhi Sharma, Suresh C. Joshi, “A Review on Bioactive Compounds and Medicinal Uses of Commiphora mukul”, Journal of Plant Sciences, Volume 7, pp. 113−137. DOI: 10.3923/jps.2012.113.137
Medicinal Plants Utilisation and Conservation 2nd Revised and Enlarged Edition Editor Prof. Pravin Chandra Trivedi Publisher: Aavishkar Publishers, Distributors Jaipur 302 003 (Raj) India
Schäfer H, Wink M (Dec 2009), “Medicinally important secondary metabolites in recombinant microorganisms or plants: progress in alkaloid biosynthesis”, Biotechnol J, Vollume 4, Issue 12, pp. 1684−1703. PMID:19946877 DOI: 10.1002/biot.200900229
Michael Wink (2006), “Importance of plant secondary metabolites for protection against insects and microbial infections Advances in Phytomedicine”, Volume 3, pp. 251−268 https://doi.org/10.1016/S1572-557X(06)03011-X
Michael Wink Plant breeding: importance of plant secondary metabolites for protection against pathogens and herbivores Theoretical and Applied Genetics (January 1988), Volume 75, Issue 2, pp. 225–233 |
Fumihiko Sato. Plant Secondary Metabolism DOI: 10.1002/9780470015902.a0001812.pub2
Zhang B (2015), “MicroRNA: a new target for improving plant tolerance to abiotic stress”, J Exp Bot. Volume 66, Issue 7, pp. 1749−1761.
Singh R, Kumar M, Mittal A, Mehta PK (2017), “Microbial metabolites in nutrition, healthcare and agriculture”, 3 Biotech. Volume 7, Issue 1, pp. 15.
Ashraf MA, Iqbal M, (2018), Chapter 8 - Environmental Stress and Secondary Metabolites in Plants: An Overview. Plant Metabolites and Regulation Under Environmental Stress, pp. 153−167. https://doi.org/10.1016/B978-0-12-812689-9.00008-X
Sulmon C, van Baaren J, Cabello-Hurtado F, Gouesbet G, Hennion F, Mony C, Renault D, Bormans M, El Amrani A, Wiegand C, Gérard C (Jul 2015), “Abiotic stressors and stress responses: What commonalities appear between species across biological organization levels?”, Environ Pollut. Volume 202, pp. 66−77. doi: 10.1016/j.envpol.2015.03.013. Epub 2015 Mar 24. Review. PubMed PMID: 25813422.
Rejeb IB, Pastor V, Mauch-Mani B (2014), “Plant Responses to Simultaneous Biotic and Abiotic Stress: Molecular Mechanisms”, Plants (Basel). Volume 3, Issue 4, pp. 458−475. Published 2014 Oct 15. doi:10.3390/plants3040458
Saddique M., Kamran M., Shahbaz M. (2018), “Differential Responses of Plants to Biotic Stress and the Role of Metabolites. Plant Metabolites and Regulation under Environmental Stress, pp. 69−87.
Cragg GM, Newman DJ (2013), “Natural products: a continuing source of novel drug leads”, Biochim Biophys Acta, Volume 1830, Issue 6, pp. 3670−3695.
Hussain MS, Fareed S, Ansari S, Rahman MA, Ahmad IZ, Saeed M (2012), “Current approaches toward production of secondary plant metabolites”, J Pharm Bioallied Sci. Volume 4, Issue 1, pp. 10−20.
Breitling R, Ceniceros A, Jankevics A, Takano E (2013), “Metabolomics for secondary metabolite research”, Metabolites, Volume 3, Issue 4, pp. 1076−1083. Published 2013 Nov 11. doi:10.3390/metabo3041076
Eibl R, Meier P, Stutz I, Schildberger D, Hühn T, Eibl D (2018), “Plant cell culture technology in the cosmetics and food industries: current state and future trends”, Appl Microbiol Biotechnol. Volume 102, Issue 20, pp. 8661−8675.
Wilson SA, Roberts SC (2011), “Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules”, Plant Biotechnol J, Volume 10, Issue 3, pp. 249−268.
Yang L, Wen KS, Ruan X, Zhao YX, Wei F, Wang Q (2018), “Response of Plant Secondary Metabolites to Environmental Factors”, Molecules, Volume 23, Issue 4, pp. 762. Published 2018 Mar 27. doi:10.3390/molecules23040762
dos Santos MD, Chen G, Almeida MC, et al. (2010), “Effects of caffeoylquinic acid derivatives and C-flavonoid from Lychnophora ericoides on in vitro inflammatory mediator production”, Nat Prod Commun, Volume 5, Issue 5, pp. 733−740.
Skrovankova S, Sumczynski D, Mlcek J, Jurikova T, Sochor J (2015), “Bioactive Compounds and Antioxidant Activity in Different Types of Berries”, Int J Mol Sci., Volume 16, Issue 10, pp. 24673−24706. Published 2015 Oct 16. doi:10.3390/ijms161024673
Del Rio D, Stalmach A, Calani L, Crozier A (2010), “Bioavailability of coffee chlorogenic acids and green tea flavan-3-ols”, Nutrients, Volume 2, Issue 8, pp. 820−833.
Monteiro M, Farah A, Perrone D, Trugo LC, Donangelo C (Oct 2007), “Chlorogenic acid compounds from coffee are differentially absorbed and metabolized in humans”, J Nutr. Volume 137, Issue 10, pp. 2196−2201. PubMed PMID: 17884997.
“National Center for Biotechnology Information”, PubChem Compound Database; CID=135, https://pubchem.ncbi.nlm.nih.gov/compound/135 (accessed Jan. 16, 2019).
Hashimoto T., Yamada Y (1994), “Alkaloid biogenesis: Molecular aspects”, Annu. Rev. Plant Biol., Volume 45, pp. 257–285. doi: 10.1146/annurev.pp.45.060194.001353.
Vincent R.M., Lopez-Meyer M., McKnight T.D., Nessler C.L (1997), “Sustained harvest of camptothecin from the leaves of Camptotheca acuminate”, J. Nat. Prod., Volume 60, pp. 618–619. doi: 10.1021/np9700228.
Gottschalk K.W. Shade (1994), “leaf growth and crown development of quercus rubra, quercus velutina, prunus serotina and acer rubrum seedlings”, Tree Physiol. Volume 14, pp. 735–749. doi: 10.1093/treephys/14.7-8-9.735.
Liu Z., Carpenter S.B., Constantin R.J. (1997), “Camptothecin production in Camptotheca acuminata seedlings in response to shading and flooding”, Can. J. Bot., Volume 75, pp. 368–373. doi: 10.1139/b97-039.
Kim OT, Jin ML, Lee DY, Jetter R (2017), “Characterization of the Asiatic Acid Glucosyltransferase”, UGT73AH1, Involved in Asiaticoside Biosynthesis in Centella asiatica (L.) Urban. Int J Mol Sci., Volume 18, Issue 12, pp. 2630. Published 2017 Dec 6. doi:10.3390/ijms18122630
Liu LF, Desai SD, Li TK, Mao Y, Sun M, Sim SP (2000), “Mechanism of action of camptothecin”, Ann N Y Acad Sci., Volume 922, pp. 1−10. Review. PubMed PMID: 11193884.
Srinivasan M, Sudheer AR, Menon VP (Mar 2007), “Ferulic Acid: therapeutic potential through its antioxidant property”, J Clin Biochem Nutr., Volume 40, Issue 2, pp. 92−100. doi: 10.3164/jcbn.40.92. PubMed PMID: 18188410; PubMed Central PMCID: PMC2127228.
Benyammi R, Paris C, Khelifi-Slaoui M, Zaoui D, Belabbassi O, Bakiri N, Meriem Aci M, Harfi B, Malik S, Makhzoum A, Desobry S, Khelifi L (Oct 2016), “Screening and kinetic studies of catharanthine and ajmalicine accumulation and their correlation with growth biomass in Catharanthus roseus hairy roots”, Pharm Biol. Volume 54, Issue 10, pp. 2033−2043. doi: 10.3109/13880209.2016.1140213. Epub 2016 Mar 17. PubMed PMID: 26983347.
Ishikawa H, Colby DA, Boger DL (2008), “Direct coupling of catharanthine and vindoline to provide vinblastine: total synthesis of (+)- and ent-(-)-vinblastine”, J Am Chem Soc. Volume 130, Issue 2, pp. 420−421.
Azevedo MI, Pereira AF, Nogueira RB, et al. (2013), “The antioxidant effects of the flavonoids rutin and quercetin inhibit oxaliplatin-induced chronic painful peripheral neuropathy”, Mol Pain. Volume 9, pp. 53. Published 2013 Oct 23. doi:10.1186/1744-8069-9-53
Bernáth J., Tétényi P (1979), “The Effect of environmental factors on growth. Development and alkaloid production of Poppy (Papaver somniferum L.): I. Responses to day-length and light intensity”, Biochem. Physiol. Pflanzen., Volume 174, pp. 468–478. doi: 10.1016/S0015-3796(17)31342-2.
Janas K.M., Cvikrová M., Pałagiewicz A., Szafranska K., Posmyk M.M (2002), “Constitutive elevated accumulation of phenylpropanoids in soybean roots at low temperature”, Plant Sci., Volume 163, pp. 369–373. doi: 10.1016/S0168-9452(02)00136-X.
Irrera N, Pizzino G, D'Anna R, et al (2017), “Dietary Management of Skin Health: The Role of Genistein. Nutrients”, Volume 9, Issue 6, pp. 622. Published 2017 Jun 17. doi:10.3390/nu9060622
Poschner S, Maier-Salamon A, Zehl M, et al. (2017), “The Impacts of Genistein and Daidzein on Estrogen Conjugations in Human Breast Cancer Cells: A Targeted Metabolomics Approach”, Front Pharmacol, Volume 8, pp. 699. Published 2017 Oct 5. doi:10.3389/fphar.2017.00699
Ping YH, Lee HC, Lee JY, Wu PH, Ho LK, Chi CW, Lu MF, Wang JJ (May 2006), “Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer”, Oncol Rep. Volume 15, Issue 5, pp. 1273−1279. PubMed PMID: 16596197.
Yang X, Nambou K, Wei L, Hua Q (Sep 2016), “Heterologous production of α-farnesene in metabolically engineered strains of Yarrowia lipolytica”, Bioresour Technol. Volume 216, pp. 1040−1048. doi: 10.1016/j.biortech.2016.06.028. Epub 2016 Jun 11. PubMed PMID: 27347651.
“National Center for Biotechnology Information”, PubChem Compound Database, CID=67249, https://pubchem.ncbi.nlm.nih.gov/compound/67249 (accessed Jan. 16, 2019).
Zobayed S.M.A., Afreen F., Kozai T (2007), “Phytochemical and physiological changes in the leaves of St. John’s wort plants under a water stress condition”, Environ. Exp. Bot., Volume 59, pp. 109–116. doi: 10.1016/j.envexpbot.2005.10.002.
Zhu Z., Liang Z., Han R., Wang X. (2009), “Impact of fertilization on drought response in the medicinal herb Bupleurum chinense DC: Growth and saikosaponin production”, Ind. Crops Prod. Volume 29, pp. 629–633. doi: 10.1016/j.indcrop.2008.08.002
Zhang BC, Li WM, Guo R, Xu YW (2012), “Salidroside decreases atherosclerotic plaque formation in low-density lipoprotein receptor-deficient mice”, Evid Based Complement Alternat Med., 607508.
Wang T, Wang C, Wu Q, Zheng K, Chen J, Lan Y, Qin Y, Mei W, Wang B. (21 Apr. 2017), “Evaluation of Tanshinone IIA Developmental Toxicity in Zebrafish Embryos”, Molecules, Volume 22, Issue 4. pii: E660. doi: 10.3390/molecules22040660. PubMed PMID: 28430131; PubMed Central PMCID: PMC6154573.
Chen W, Lu Y, Chen G, Huang S (2013), “Molecular evidence of cryptotanshinone for treatment and prevention of human cancer”, Anticancer Agents Med Chem., Volume 13, Issue 7, pp. 979−987.
Park JY, Lee YK, Lee DS, Yoo JE, Shin MS, Yamabe N, Kim SN, Lee S, Kim KH, Lee HJ, Roh SS, Kang KS (May 2017), “Abietic acid isolated from pine resin (Resina Pini) enhances angiogenesis in HUVECs and accelerates cutaneous wound healing in mice”, J Ethnopharmacol, Volume 5, Issue 203, pp. 279−287. doi: 10.1016/j.jep.2017.03.055. Epub 2017 Apr 4. PubMed PMID: 28389357.
Refbacks
- There are currently no refbacks.